abstract：AIMS:We conducted this study to investigate the independent association of medial temporal atrophy (MTA) and white matter hyperintensities (WMH) with cognitive impairments of Alzheimer's disease (AD) patients and the interaction between MTA and WMH. METHODS:From 13 centers, a total of 216 AD patients were consecutivel...

journal_title：European neurology

authors： Shim YS,Youn YC,Na DL,Kim SY,Cheong HK,Moon SY,Park KW,Ku BD,Lee JY,Jeong JH,Kang H,Kim EJ,Lee JS,Go SM,Kim SH,Cha KR,Seo SW

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the plasma levels of factor VIII (FVIII), von Willebrand factor (vWF) and their association in patients with cerebral venous sinus thrombosis (CVST). METHODS:We prospectively included 25 CVST patients admitted to the university hospital and 53 voluntary subjects as a cont...

journal_title：European neurology

authors： Shahsavarzadeh T,Javanmard SH,Saadatnia M

更新日期：2011-01-01 00:00:00

abstract：AIM:To investigate whether writing errors are predictive of longitudinal brain atrophy progression in patients with amyotrophic lateral sclerosis (ALS). METHODS:The frequency of writing errors in 6 ALS patients without dementia was compared with longitudinal changes in lateral ventricular areas of the bilateral anteri...

journal_title：European neurology

authors： Ichikawa H,Ohno H,Murakami H,Ohnaka Y,Kawamura M

更新日期：2011-01-01 00:00:00

abstract：:The European Association of Young Neurologists and Trainees (EAYNT) is a non-profit organization which acts on behalf of young neurologists in Europe and concertedly exerts influence on the formation of a new generation of neurologists [Struhal et al.: Eur J Neurol 2009;16:e146-e148]. This concerns particularly the Ge...

journal_title：European neurology

authors： Struhal W,Falup-Pecurariu C,Sztriha LK,Grisold W,Sellner J

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Mood disorder is a frequent complication of stroke. Comorbid depressive and anxiety disorders are very common, indicating that it is advisable to assess both disorders at the same time. The aim of the present study was to examine the prevalence of post-stroke depression (PSD) and poststroke anxiety (PSA) at ...

journal_title：European neurology

authors： Kim JT,Park MS,Yoon GJ,Jung HJ,Choi KH,Nam TS,Lee SH,Choi SM,Kim BC,Kim MK,Cho KH

更新日期：2011-01-01 00:00:00

abstract：:While Alfred Vulpian (1826-1887) is not completely forgotten, he cannot match the uninterrupted celebrity which Jean-Martin Charcot (1825-1893) still enjoys today. After becoming interne (residents) at the same institute in 1848, both were involved in shaping the cradle of what would become modern neurology. Both star...

journal_title：European neurology

authors： Bogousslavsky J,Walusinski O,Moulin T

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:We attempted to investigate changes of the pedunculopontine nucleus (PPN) according to walking ability in chronic stroke patients, using diffusion tensor imaging (DTI). METHODS:55 consecutive chronic stroke patients who were not able to walk due to injury of the corticospinal tract (CST) at stroke onset and...

journal_title：European neurology

authors： Yeo SS,Ahn SH,Choi BY,Chang CH,Lee J,Jang SH

更新日期：2011-01-01 00:00:00

abstract：:Direct evidence of the anatomical localization of brain function is provided by functional neurological changes during awake surgery combined with data from preoperative functional magnetic resonance imaging and diffusion tensor imaging studies. The goal of the present study was to analyze the etiology and mechanism o...

journal_title：European neurology

authors： Shinoura N,Yoshida M,Yamada R,Tabei Y,Saito K,Suzuki Y,Yagi K

更新日期：2010-01-01 00:00:00

abstract：:Camptocormia (bent spine syndrome, cyphose hystérique) is an abnormality characterized by severe forward flexion of the thoracolumbar spine which typically increases during walking or standing and completely disappears in supine position. Camptocormia can be due to central nervous system diseases, such as Parkinson's ...

journal_title：European neurology

authors： Finsterer J,Strobl W

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:We prospectively assessed the frequency, type, severity and cause of treatment among the long-term residents of the Kork Epilepsy Centre in the year 2005. METHODS:All long-term residents were exclusively referred to the general surgeon practicing on the campus. Patients were divided into 2 groups compr...

journal_title：European neurology

authors： Steinhoff BJ,Hartmann R,Luy M,Rombach A,Ziegler G,Schulte-Mönting J,Gilliam FG

更新日期：2010-01-01 00:00:00

abstract：:The aim of this work was to quantify the accumulation of iron in the basal ganglia in multiple sclerosis (MS) patients and in a control group, and to investigate the relationship between iron accumulation and other parameters assessed in MS, i.e. lesion load (LL) and brain parenchymal fraction (BPF). Magnetic resonanc...

journal_title：European neurology

authors： Burgetova A,Seidl Z,Krasensky J,Horakova D,Vaneckova M

更新日期：2010-01-01 00:00:00

abstract：AIMS:To perform a large and detailed epidemiologic study on restless legs syndrome (RLS) during pregnancy in a European country. METHODS:A cross-sectional questionnaire survey. The questionnaire was distributed by the medical staff in different outpatient waiting rooms (obstetrics and gynecology department of the univ...

journal_title：European neurology

authors： Neau JP,Porcheron A,Mathis S,Julian A,Meurice JC,Paquereau J,Godeneche G,Ciron J,Bouche G

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Half of Parkinson's disease (PD) patients with mild cognitive impairment (MCI) develop dementia. We studied topographic distribution of cerebral hypometabolism in PD with different types of MCI. METHODS:This study included 61 nondemented PD patients and 14 age-matched controls. PD patients were grouped into...

journal_title：European neurology

authors： Lyoo CH,Jeong Y,Ryu YH,Rinne JO,Lee MS

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:Cerebral arteriovenous malformations (AVMs) harbor a network of abnormal vasculatures, namely the nidus between arterial and venous components. The pressure gradient between these two components results in abnormal high-velocity arteriovenous shunts flowing through the nidus and alternate intracranial hemody...

journal_title：European neurology

authors： Chuang YM,Guo W,Lin CP

更新日期：2010-01-01 00:00:00

abstract：:The aim of this study was to assess the impact of cardiac autonomic derangement on gender-associated functional outcome of patients with subacute ischemic stroke undergoing a hospital-based rehabilitation program. The study population included 126 consecutive first-ever stroke survivors (mean age 59.7 +/- 11.6 years)....

journal_title：European neurology

authors： Bassi A,Colivicchi F,Santini M,Caltagirone C

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data on the association between renal dysfunction and outcome in patients with stroke are controversial and scarce. We investigated the predictors of renal dysfunction upon admission and the association between renal dysfunction and clinical outcome in patients with acute stroke in a hospitalized...

journal_title：European neurology

authors： Hao Z,Wu B,Lin S,Kong FY,Tao WD,Wang DR,Liu M

更新日期：2010-01-01 00:00:00

abstract：:Deficits in the cholinergic system are pronounced in dementia with Lewy bodies (DLB) and are more severe in patients with visual hallucinations (VHs). The aim is to identify the occipital glucose metabolism patterns by positron emission tomography (PET) and the changes following donepezil treatment. 13 DLB patients wi...

journal_title：European neurology

authors： Satoh M,Ishikawa H,Meguro K,Kasuya M,Ishii H,Yamaguchi S

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To investigate clinical and magnetic resonance imaging (MRI) features of Wernicke's encephalopathy with cortical abnormalities (WEc). METHODS:We retrospectively evaluated the clinical features and MRI findings in 3 cases of WEc in comparison with those of 7 previously reported cases. RESULTS:Besides the cla...

journal_title：European neurology

authors： Sakurai K,Sasaki S,Hara M,Yamawaki T,Shibamoto Y

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:Whereas insomnia is frequent in restless legs syndrome (RLS), little is known about daytime sleepiness. We studied a series of 27 consecutive patients with idiopathic RLS in order to identify the characteristics and evolution of excessive daytime sleepiness (EDS) under dopaminergic treatment. METHODS:P...

journal_title：European neurology

authors： Kallweit U,Siccoli MM,Poryazova R,Werth E,Bassetti CL

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The meningitides are rare but well-identified complications in patients with systemic lupus erythematosus (SLE). AIMS:To determine the clinical characteristics, risk factors, prevalence and outcomes of the meningitides (septic and aseptic) in patients with SLE. PATIENTS AND METHODS:From January 1988 to Dec...

journal_title：European neurology

authors： Baizabal-Carvallo JF,Delgadillo-Márquez G,Estañol B,García-Ramos G

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:To evaluate the role of some sex hormones in migraine headaches, the aim of this study was to assess the prevalence and characteristics of headache, especially migraine, in patients with polycystic ovary syndrome (PCO) compared with women without this disease. METHODS:One hundred and thirty-three women with...

journal_title：European neurology

authors： Pourabolghasem S,Najmi S,Arami MA

更新日期：2009-01-01 00:00:00

abstract：:In recent years, the involvement of the immune system in acquired forms of cerebellar ataxia has been frequently demonstrated. In this study, we describe 6 out of 49 patients with subacute or chronic progressive cerebellar ataxia in whom antibodies against neuronal and non-neuronal antigens were identified. Two women ...

journal_title：European neurology

authors： Fancellu R,Pareyson D,Corsini E,Salsano E,Laurà M,Bernardi G,Antozzi C,Andreetta F,Colecchia M,Di Donato S,Mariotti C

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the influence of psychosocial variables on patients with multiple sclerosis (MS) and the relationship between these variables and the onset of MS. BACKGROUND:The current evidence indicates that many types of psychosocial factors are involved in the development and rel...

journal_title：European neurology

authors： Liu XJ,Ye HX,Li WP,Dai R,Chen D,Jin M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The biological mechanisms by which cerebral aneurysms emerge, enlarge and rupture are not totally understood. In the present study, we analyzed the genome-wide gene expression profile in human intracranial aneurysms using cDNA microarrays. METHODS:Affymetrix HU133 Plus 2.0 microarrays were used to compare g...

journal_title：European neurology

authors： Li L,Yang X,Jiang F,Dusting GJ,Wu Z

更新日期：2009-01-01 00:00:00

abstract：:The child prodigy Marie-Jean-Pierre Flourens received his medical degree at Montpellier when aged 19. As a young promising physician Flourens was asked to investigate Gall's controversial views on cerebral localization. To test Gall's assertions, Flourens developed ablation as a procedure to explore the workings of th...

journal_title：European neurology

authors： Pearce JM

更新日期：2009-01-01 00:00:00

abstract：:About one third of patients with newly diagnosed epilepsy do not achieve seizure control despite medical therapy and should be assessed in detail to confirm the diagnosis, to determine the epilepsy syndrome and to plan treatment strategy. Refractory epilepsy is established when there is inadequate seizure control desp...

journal_title：European neurology

authors： Beleza P

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:We investigated the predictive value of standard neurological evaluation, a commercially available biomarker assay and neuroimaging in the subacute phase for outcome after thrombolytic therapy in ischemic stroke. METHODS:Thirty-four consecutive ischemic stroke patients were evaluated by means of the NIH S...

journal_title：European neurology

authors： Brouns R,Sheorajpanday R,Kunnen J,De Surgeloose D,De Deyn PP

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Central pontine myelinolysis (CPM)/extrapontine myelinolysis (EPM) is one of the most serious neurological complications that can occur after orthotopic liver transplantation (OLT). We analyzed the risk factors for CPM/EPM in OLT patients. METHODS:We retrospectively reviewed the records of 1,247 patients wh...

journal_title：European neurology

authors： Lee EM,Kang JK,Yun SC,Kim KH,Kim SJ,Hwang KS,Lee SG

更新日期：2009-01-01 00:00:00

abstract：:The management of early Parkinson's disease (PD) involves the treatment of motor symptoms and, increasingly, non-motor symptoms. Given the fast pace of clinical research in PD, clinicians are faced with the challenge of integrating the latest findings into the ongoing care of individual PD patients. Part 1 of this 2-p...

journal_title：European neurology

authors： Simuni T,Lyons KE,Pahwa R,Hauser RA,Comella C,Elmer L,Weintraub D

更新日期：2009-01-01 00:00:00

abstract：:The polymath William Rivers played an important role in his work with Henry Head in demonstrating the varied, evolving patterns of sensory loss, and epicritic and protopathic sensation, after the section of the superficial ramus of Head's left radial nerve. After a mixed and frustrated army career Rivers devoted his a...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：UNLABELLED:Intracranial angioplasty stenting may be an efficient therapy in patients with intracranial atherosclerotic symptomatic vertebrobasilar artery stenosis unresponsive to optimal medical therapy. We present our experience in this setting. RESULTS:The study included 12 cases (8 men, 4 women), with an age range ...

journal_title：European neurology

authors： Ralea IC,Nighoghossian N,Tahon F,Derex L,Cakmak S,Trouillas P,Turjman F

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIM:Although most late-onset seizures (LS) appear within 2 years after stroke, some of them occur later and their characteristics are unknown. The aim of this study was to compare the characteristics of patients with very-late-onset seizures (VLS) to those with early-onset seizures (ES) and those with LS. P...

journal_title：European neurology

authors： De Reuck J,Sieben A,Van Maele G

更新日期：2008-01-01 00:00:00

abstract：:Percussion of the skull dates from a time when there were virtually no radiological methods for examining the skull and brain. Three apparently independent contributions appeared within the years 1893-1895. The sound elicited, tenderness, and auscultatory percussion have each been employed for diagnostic purposes, but...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:The association of anaemia and gastro-intestinal abnormalities with disorders of the brain, spinal cord, and peripheral nerves has been recognized since the mid 19th century. In early reports interpretable as subacute combined degeneration, anaemia was overlooked, and conversely in Addison's and other early reports of...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:We report on management strategies and clinical outcomes in 4 cases of acute symptomatic congestive intracranial hypertension associated with cerebral arteriovenous malformations (AVMs). Congestion resulted from high-volume shunts exhausting the drainage capacity of the cerebral venous system in 3 patients, and from s...

journal_title：European neurology

authors： Rosenkranz M,Regelsberger J,Zeumer H,Grzyska U

更新日期：2008-01-01 00:00:00

abstract：AIMS:This study was designed to investigate if folate treatment is able to reverse the phenytoin-induced deficiency of salivary immunoglobulin A (IgA). METHODS AND MATERIAL:Twenty-five epileptic patients who had been under phenytoin therapy for at least the last 6 months were randomly selected and subjected to folic a...

journal_title：European neurology

authors： Zare M,Ghazvini MR,Yazdi HR,Nezhad VS,Chitsaz A

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND/AIM:In this case-control study, our aim was to check for a possible independent role of hypertension in increasing the risk of developing Bell's palsy. METHODS:All patients diagnosed as having Bell's palsy referred to a neurology clinic were enrolled as cases. Controls were selected among other patients ref...

journal_title：European neurology

authors： Savadi-Oskouei D,Abedi A,Sadeghi-Bazargani H

更新日期：2008-01-01 00:00:00

abstract：:The blink reflex and its equivalent glabella tap reflex are behavioural motor responses normally found in neonates and in the physiological startle reflex. Historically, it was described by Overend in 1896 and soon afterwards by McCarthy and by Bekhterev who disputed its origins. Kugelberg in 1952 recorded the early-l...

journal_title：European neurology

authors： Pearce JM

更新日期：2008-01-01 00:00:00

abstract：:We present a long-term follow-up examination concerning patients with isolated extra-ocular muscle involvement in thyroid-related orbitopathy. Within the previous 13 years we observed 7 patients with endocrine orbitopathy and marked myopathy of the extra-ocular muscles. Five of these patients had no detectable proptos...

journal_title：European neurology

authors： Gerlach M,Ferbert A

更新日期：2008-01-01 00:00:00

abstract：:Fatigue is one of the most frequent and most disabling symptoms in multiple sclerosis (MS). We investigated the possible association of the MS-related fatigue syndrome with the available disease-modifying therapies and the main disease characteristics in a cross-sectional study on 320 consecutive patients. The prevale...

journal_title：European neurology

authors： Putzki N,Katsarava Z,Vago S,Diener HC,Limmroth V

更新日期：2008-01-01 00:00:00